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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CDKL1
All Species:
0
Human Site:
S105
Identified Species:
0
UniProt:
Q00532
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q00532
NP_004187.2
357
41671
S105
V
P
E
H
L
V
K
S
I
T
W
Q
T
L
Q
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001100233
358
41783
Dog
Lupus familis
XP_851358
367
42581
Cat
Felis silvestris
Mouse
Mus musculus
Q8CEQ0
352
41005
Rat
Rattus norvegicus
Q66HE7
352
40881
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514378
352
40807
Chicken
Gallus gallus
P13863
303
34670
Frog
Xenopus laevis
P35567
302
34487
Zebra Danio
Brachydanio rerio
Q6AXJ9
350
40792
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_608950
501
57855
Honey Bee
Apis mellifera
XP_394980
385
44993
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_787618
363
41882
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P23111
294
33816
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P24100
294
34012
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
97.7
88.5
N.A.
88.8
88.2
N.A.
86.5
37.8
36.9
77
N.A.
43.1
53.2
N.A.
59.5
Protein Similarity:
100
N.A.
99.1
92.6
N.A.
92.7
93
N.A.
92.7
52.3
54.6
87.9
N.A.
54.6
69.6
N.A.
73
P-Site Identity:
100
N.A.
0
0
N.A.
0
0
N.A.
0
0
0
0
N.A.
0
0
N.A.
0
P-Site Similarity:
100
N.A.
0
0
N.A.
0
0
N.A.
0
0
0
0
N.A.
0
0
N.A.
0
Percent
Protein Identity:
N.A.
34.4
N.A.
33
N.A.
N.A.
Protein Similarity:
N.A.
54.3
N.A.
54.6
N.A.
N.A.
P-Site Identity:
N.A.
0
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
0
N.A.
0
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
100
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
100
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
100
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
100
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
100
0
0
0
0
0
0
0
0
100
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
100
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
100
0
0
100
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
100
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
100
0
0
100
0
0
% T
% Val:
100
0
0
0
0
100
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
100
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _